Protein Modification Reagents
![eMolecules 2112731-52-7 | N-(Azido-PEG3)-N-Boc-PEG3-acid | Broadpharm | MFCD30723234 | 522.596 | C22H42N4O10 | 98.000 | CC(C)(C)OC(=O)N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(O)=O | 500mg | 343283696](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203406.JPG-250.jpg)
eMolecules 2112731-52-7 | N-(Azido-PEG3)-N-Boc-PEG3-acid | Broadpharm | MFCD30723234 | 522.596 | C22H42N4O10 | 98.000 | CC(C)(C)OC(=O)N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(O)=O | 500mg | 343283696
N-(Azido-PEG3)-N-Boc-PEG3-acid | Broadpharm | 2112731-52-7 | MFCD30723234 | 522.596 | C22H42N4O10 | 98.000 | CC(C)(C)OC(=O)N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(O)=O | 500mg | 343283696
Medchemexpress LLC DSPE-PEG-CHO (aldehyde-terminated DSPE-PEG) | 2000 (average) | 10 MG
DSPE-PEG-CHO (MW 2000) is a heterobifunctional PEGylated phospholipid composed of a DSPE lipid anchor linked to a polyethylene glycol chain terminated with an aldehyde group. Supplied as a powder, it is designed for introducing reactive aldehyde functionality onto liposomes, lipid nanoparticles, or other lipid-based carriers to enable conjugation of biomolecules for targeted delivery and surface modification.
- Aldehyde-terminated PEG enables covalent conjugation to primary amines.
- PEG MW 2000 provides hydrophilicity and steric stabilization of particles.
- DSPE lipid anchor facilitates efficient incorporation into lipid bilayers and nanoparticles.
- DMSO solubility approximately 12.5 mg/mL with ultrasonic warming to 60°C.
- Powder storage at -20°C (up to 3 years); in solvent storage at -80°C for 6 months or -20°C for 1 month.
Medchemexpress LLC 4-Arm PEG-SCM MW 20 100mg
4-Arm PEG-SCM (MW 20000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery[1]
Medchemexpress LLC N3-PEG11-CH2CH2Br | 2098982-00-2 | MFCD32696701 | 99.8% | 634.56 g/mol | C24H48BrN3O11 | 50 MG
N3-PEG11-CH2CH2Br is a polyethylene glycol (PEG11) linker with an azide (N3) terminus and a bromide-functionalized ethylene spacer. It is a hydrophilic, viscous liquid used in bioconjugation and click-chemistry workflows to improve aqueous solubility and provide a reactive bromide handle for further modification.
- Azide-terminated PEG11 linker for click chemistry.
- Bromide-functionalized ethylene spacer provides a reactive handle.
- Hydrophilic PEG spacer increases solubility in aqueous media.
- High purity suitable for research applications.
- Recommended storage conditions maintain stability.
Mitegen PEG 6000, 50%(w/v), 250 ml, CAS# 25322-68-3
Use our stock solutions directly or as a component in solutions you create in your own lab. We prepare our stock solutions using high quality raw materials, ASTM Type 1 water, and sterile packaging. Our stock solutions are intended for Research and Development Use Only.
Medchemexpress LLC DSPE-PEG-SH | 1462982-18-8 | 90.0% | 1,000 Da | C44H86NO10PS | 250 MG
DSPE-PEG-SH (MW 1000) is a thiol-terminated PEGylated phospholipid reagent used to introduce free thiol groups onto liposome or nanoparticle surfaces for subsequent bioconjugation. It is supplied for research use in small laboratory pack sizes and is commonly employed in formulation, surface modification, and targeted delivery workflows.
- Thiol functional group for conjugation to maleimide reagents.
- Average molecular weight of approximately 1,000 Da.
- Amphiphilic phospholipid-PEG structure for incorporation into lipid bilayers.
- Enables surface modification of liposomes and nanoparticles.
- Supplied in small research pack sizes for laboratory use.
- Typical reported purity around 90%.
Medchemexpress LLC (S,R,S)-AHPC-PEG2-C4-Cl | 1835705-57-1 | MFCD31560480 | 98.2% | 651.26 g/mol | C32H47ClN4O6S | 2 G
A VHL ligand-linker conjugate used as a PROTAC building block; it incorporates the (S,R,S)-AHPC VHL ligand connected via a PEG2-C4 alkyl/ether linker with a terminal chloride and has been reported to induce degradation of GFP-HaloTag7 in cell-based assays.
- Used as a building block for PROTAC synthesis and E3 ligase ligand-linker conjugates.
- Contains a VHL-binding (S,R,S)-AHPC motif with a PEG2-C4 linker.
- Reported to induce GFP-HaloTag7 degradation in cell assays.
- Soluble in DMSO, water, and ethanol at approximately 50 mg/mL (may require ultrasonic).
- Available in multiple package sizes, including a 2 g option.
Medchemexpress LLC Azido-AHPC-PEG3 (VHL ligand-linker) pyrrolidine-2-carboxamide | 1797406-80-4 | MFCD31807299 | ≥95.0% | 645.77 g/mol | C30H43N7O7S | 10 MG
(S,R,S)-AHPC-PEG3-N3 is an E3 ligase ligand-linker conjugate that couples an (S,R,S)-AHPC VHL-binding motif to a three-unit PEG linker terminated with an azide. It is intended as a click-chemistry reagent for PROTAC synthesis and bioconjugation, enabling covalent linkage to alkyne-bearing partners.
- Molecular weight 645.77 g/mol.
- Chemical formula C30H43N7O7S.
- CAS number 1797406-80-4.
- Purity ≥95%.
- Suitable for CuAAC and SPAAC click reactions.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Soluble in ethanol, water, and DMSO at concentrations commonly used for bioconjugation.
Nanocs Biotin PEG Maleimide, 100mg
Purity: >95%, Solubility: Soluble in water, Biotin PEG Maleimide is one of Nanocs pegylated Biotinylation reagents with an activated maleimide group. Maleimide is able to react with thiol/sulfhydryl groups rapidly and specifically at neutral pH. Reaction between maleimide and thiol group enables fast conjugation of biotin tag to targeted molecules or material surfaces. Resulted biotin moiety can bind to avidin or streptavidin with high affinity. PEG linker between biotin and maleimide offers better water solubility, reduced steric hydrance and enhanced stability.
Medchemexpress LLC Nh2-peg4-dota | 2090232-34-9 | 97.0% | 622.71 g/mol | C26H50N6O11 | 50mg
NH2-PEG4-DOTA is a bifunctional DOTA-type metal chelator NH2-PEG4-DOTA can be conjugated with Dextran for quantitative analysis in the presence of a highly luminescent complex NH2-PEG4-DOTA can also bind to radionuclides to prepare radionuclide drug conjugates (RDCs) RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy
Medchemexpress LLC Azide-PEG4-VC-PAB-doxorubicin | 99.6% | 1222.25 g/mol | C57H75N9O21 | 100 MG
Azide-PEG4-VC-PAB-doxorubicin is an azide-functionalized drug-linker conjugate that links the cytotoxic agent doxorubicin to a PEG4-VC-PAB linker for use in antibody-drug conjugate synthesis and click chemistry applications.
- High purity (99.62%).
- Molecular weight 1222.25 g/mol.
- Chemical formula C57H75N9O21.
- Orange to red solid appearance.
- Storage: powder at -20°C (long term) or 4°C (short term); in solvent at -80°C or -20°C as recommended.
- Available as solid (1-100 mg) and 10 mM solution in DMSO.
eMolecules 459426-22-3 | Medchem Express | Biotin-PEG4-NHS ester | 50mg | 527574014 | HY-140889 | MFCD08458915 | 588.67 | C25H40N4O10S
Ambeed | (S)-tert-Butyl 2-methylpiperazine-1-carboxylate hydrochloride | 1g | 552587486 | A149133 | 960283-58-3 | MFCD11101258 | 236.740 | C10H21ClN2O2
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